Dermal fillers like Restylane and Botox are the most popular non-surgical cosmetic treatment in the world. They are FDA approved and used to reduce the appearance of wrinkles and folds on the skin.

What is Botox?

Botox is the most popular non-surgical cosmetic treatment. More than 6 million people have Botox treatments performed every year.

Botox is a neurotoxin used to reduce fine lines and wrinkles. It does this by paralyzing the muscled under the skin, causing them to relax and the skin above them to un-wrinkle. It can also be used to treat excessive sweating, headaches, migraines, and some muscle and organ disorders.

When treating fine lines and wrinkles, it is administered via injection.

What is Restylane?

Restylane is a dermal filler made from “non-animal stabilized hyaluronic acid” or NASHA, for short. Similar to Botox, Restylane is injected at a mid-to-deep level and used for correction of moderate to deep facial wrinkles and folds.

Restylane works by attracting and binding itself to water molecules. This causes a volumizing effect in the dermal tissue. Over time, Restylane is degraded by the body’s natural mechanisms. It will disappear without any left-over residue. If you want to maintain the look, you will have to “refresh” approximately once every 6 months.

Nasolabial folds are an example of folds treated by Restylane.

Restylane is also used as a lip filler due to its volumizing aspect. Many patients come to our offices in Chicago with the hope of being able to even out their lips or plump them up. In the case study below, you will see a patient who accomplished that.

Difference between Botox and Restylane

So, the difference between Botox and Restylane is the way they work. Botox relaxes the muscles under the skin, reducing the appearance of wrinkles. Restylane volumizes from under the skin, also reducing wrinkles, but in the opposite way.

Restylane Case Study

One of our beautiful patients wanted to even out her lips because the right upper and lower lips were a bit smaller on one side than the other. Restylane as a lip filler is perfect for this because it adds volume. Restylane was injected on the right upper and lower lips to help even them out.

Before lip filler lips slightly asymmetrical

This photo was taken before lip filler. (Taken 3/28/2019)

After lip filler lips more even / symmetrical

This photo was taken after Restylane lip filler. Restylane-L (0.5cc) was injected only to the right upper and lower lips to even them out with the left side. (Taken 4/11/2019)

Face fillers and Botox Case Study

Botox was used for the forehead, frown line, and brows for a brow lift. The patient also had Restylane-L to the nasolabial folds and lips. Restylane Defyne ((0.8cc) was used for the midface and temples.

These images were taken before Botox and Restylane treatments.

These images were taken after Botox and Restylane were used in conjunction to reduce wrinkles and add volume in desired areas.


By combining both Botox and Restylane treatments, Chicago Cosmetic Institute was able to help Kasia bring symmetry to her lips, lift her brow, and reduce the appearance of frown lines and nasolabial folds.

Sometimes the best treatment combines different dermal fillers to perform multiple tasks.

If you are interested in learning more about how dermal fillers like Botox and Restylane can help you bring your desired appearance to life, get in touch with Chicago Cosmetic Institute for a consultation. Together with a doctor, you can employ the perfect combination of treatments to achieve desired results.


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Chicago Cosmetic Institute: Med Spa Services The Chicago Cosmetic Institute offers a variety of medical spa services, also known as med spa services. We have a variety of options that focus on the eyes, face, breast, body, and the skin. Our caring and results-oriented team strives for patient satisfaction. Book a consultation today to learn about options that help you feel your best. Our Chicago Med Spa Services include: Laser Hair Removal, Tummy Tuck services, Liposuction, Botox, Lifestyle Lift Beyond cosmetic services and plastic surgery, our team of medical estheticians, physicians, and their support staff can help you with additional services, including: acne treatment options, a chemical peel, skin tightening procedures, stretch mark removal, and other skin care services that look and feel great.

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